MTN Lions head coach Johan Ackermann has announced his side to front The Sharks at Ellis Park on Friday evening.
Francois du Toit, Julian Redelinghuys, Warwick Tecklenburg and Ross Cronje all move up into the starting line-up, while Chrysander Botha returns at fullback after his stint with the Namibian national side.
Meanwhile, on the bench, the MTN Lions welcome Lambert Groenewald who the GLRU has recently contracted.
The match will get under way at 19:10 while gates open from 14:00. There will be two curtain-raisers played between the MTN Golden Lions (B) and the Griffons, at 14:00, and between club outfits Harlequins and Kansas Jayhawks (USA), at 16:15.
MTN Lions: 1. JC Janse van Rensburg (Captain), 2. Francois du Toit, 3. Julian Redelinghuys, 4. Hendrik Roodt, 5. Hugo Kloppers, 6. Warwick Tecklenburg, 7. Derick Minnie, 8. Willie Britz, 9. Ross Cronje, 10. Marnitz Boshoff, 11. Anthony Volmink, 12. Alwyn Hollenbach, 13. Stokkies Hanekom, 14. Ruan Combrinck, 15. Chrysander Botha
Replacements: 16. Robbie Coetzee, 17. CJ van der Linde, 18. Gavin Annandale, 19. Lambert Groenewald, 20. Michael Bondesio, 21. Dylan des Fountain, 22. Deon van Rensburg